Wall Street ends down sharply after Fed minutes

TORONTO, Feb 20 (Reuters) - Canada's Rebecca Marino, a rising star in women's tennis, stepped away from the sport in search of a normal life on Wednesday, weary of battling depression and cyber-bullies. Ranked number 38 in the world two years ago, the 22-year-old admitted she had long suffered from depression and was no longer willing to make the sacrifices necessary to reach the top. "After thinking long and hard, I do not have the passion or enjoyment to drive myself to the level I would like to be at in professional tennis," Marino explained in a conference call. ...
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Egypts Floods Smuggling Tunnels to Gaza With Sewage


Hatem Moussa/Associated Press


A Palestinian clearing a tunnel of sewage in Rafah, between Egypt and the southern Gaza Strip.







GAZA —The Egyptian military is resorting to a pungent new tactic to shut down the smuggling tunnels connecting Sinai and Gaza: flooding them with sewage. Along with the stink, the approach is raising new questions about relations between Egypt’s new Islamist leaders and their ideological allies in Hamas who control the Gaza Strip.




“Awful,” said Abu Mutair Shalouf, 35, a Palestinian smuggler on the Gaza side, watching workers haul buckets of sewage-soaked soil from the shaft of a tunnel flooded by the Egyptian military 15 days ago. “I don’t know why they did this.”


Advisers to the Egyptian president, Mohamed Morsi, a leader of the Muslim Brotherhood’s political arm, say the answer is simple: they are determined to shut the tunnels to block the destabilizing flow of weapons and militants into Sinai from Gaza — a vow Mr. Morsi made with evident passion in an interview five months ago.


And the more muted response from Hamas, a militant offshoot of the Brotherhood, is the strongest indication yet that its leaders are now pinning their hopes on their ideological allies in Cairo, even if at the moment they appear to be harming the interests of the citizens of Gaza. The tunnels remain a vital source of certain imports to Gaza and smuggling-tax revenue for Hamas, and when the former president, Hosni Mubarak, used far less effective methods to close the tunnels, Hamas screamed of betrayal.


After the sewage flooding, several Hamas officials instead emphasized Egypt’s right to protect its borders as it chose. “Egypt is a state of sovereignty and we do not impose on it anything,” said Salah al-Bardawil, a Hamas official in Gaza. “We address the Egyptian side about the issue and hope they will understand us and our needs,” he added. “We trust the Egyptian leadership that they will not leave the Palestinian people alone.”


Analysts offer many theories about the timing. At a moment of political and economic difficulties, with a financial aid package stalled in the United States Congress, Egypt’s Islamist-led government “is showing itself once more as a valuable ally,” speculated Yasser el-Shimy, Egypt analyst at the International Crisis Group. “It can do something like this, which, perhaps, promotes strategic interests.”


Or perhaps, Mr. Shimy said, Mr. Morsi’s government aimed to remind Israel that it, and not Egypt, still bore responsibility for Gaza’s poverty and problems. Or perhaps the Egyptian military was sending some domestic message of its own, either to the Brotherhood or other domestic constituents, about the generals’ independence from the Islamists.


Concern in Cairo about the tunnels spiked last August, when 16 Egyptian soldiers died in a militant attack on a military outpost in Sinai. The Egyptian government believes the attackers came through the tunnels.


Then, after Egypt helped broker a truce between Hamas and Israel to end a week of fighting in Gaza last November, Israel eased restrictions on imports over the border. Most notably, it began allowing in more construction material previously considered to have a potential military use, though Palestinians say the Israelis still block steel and other materials.


Essam el-Hadded, Mr. Morsi’s national security adviser, suggested this week that the loosened restrictions at the border crossing might have encouraged the crackdown on tunnels. “Now we can say that the borders are open to a good extent — it could still be improved — and the needs of the Gazan people are allowed in,” Mr. Hadded told Reuters.


Under Mr. Mubarak, Palestinians said, the Egyptians sometimes flooded tunnels with gas, which was easily remedied by pumping in air.


But around the beginning of February the Egyptian military began for the first time to use waste water instead, eventually flooding about two dozen of the 200-odd tunnels. (The Egyptian authorities say there are 225; Palestinians say 250.)


Mr. Shalouf, 35, who imported mainly gravel, said that before removing the buckets of dirt he had pumped out the water. Now he plans to lay down sand and sawdust and reinforce the ceiling. Repairs could take three weeks.


Palestinians say that so far the flooding has hurt individual livelihoods but not the total volume of goods moving below ground. On Wednesday, about two cargo trucks per minute were pulling out of the main smuggling zone inside Gaza, laden with cement, gravel, canned food, citrus and vegetables. Hamas customs officers kept a record of each truck and load.


Fares Akram reported from Gaza, and David D. Kirkpatrick from Cairo. Mayy El-Sheikh contributed reporting from Cairo.



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Sony’s “Evolution of PlayStation” Videos Lead Up to Wednesday’s Event






Sony‘s PlayStation brand has been around almost 20 years now, in the United States. And in anticipation of its Wednesday “#PlayStation2013″ event, at which it is widely expected to unveil its next-generation PlayStation console, Sony has published a series of “Evolution of PlayStation” videos on YouTube and its own site. These videos present a (somewhat one-sided) history of the PlayStation brand, and its consoles and major highlights through the years.


Here’s a timeline with links to the videos, for those who could use the recap:






1994 — The First PlayStation


That’s what it was called: Just “PlayStation.” Launching at $ 299, $ 100 less than the competing Sega Saturn, the Sony PlayStation — originally developed as a CD drive add-on to one of Nintendo’s consoles — soon became a major force in the video game industry.


Partway through the PlayStation’s lifecycle, the DualShock controller added twin analog sticks and a built-in vibration feature, echoing similar features found on Nintendo and Sega’s consoles. Meanwhile, the hard-to-find black Net Yaroze PlayStation console let people make their own games.


Sony would continue to sell slim, redesigned “PSone” consoles during the PlayStation 2‘s heyday, until production was finally stopped in 2006.


2000 — The PlayStation 2


Known as the PS2, Sony’s next PlayStation would go on to become the best-selling game console of all time, with more than 150 million sold. Production of new PlayStation 2 consoles just stopped this January, and while some PS2 games have received HD re-releases on the PlayStation 3 the vast majority can’t be played on Sony’s current console.


The PS2 played new games designed for its “Emotion Engine” processor, and could improve the graphics of PSone games played on it. It also played DVD movies, and the original large PS2 had optional network and hard disk add-ons, which let enthusiasts install Linux on it or play online games like Final Fantasy XI. (The “slim” PS2 has built-in networking capability, but can’t be upgraded with a hard disk.)


2006 — The PlayStation 3


The PS3′s disastrous North American launch became a veritable fountain of memes, as Sony showmen’s lines were quoted and remixed endlessly afterwards. Sony exec (now CEO) Kaz Hirai’s announcement of the PS3′s launch price tag — “$ 599 U.S. dollars!” — was met with stunned silence, and the console debuted to mediocre sales numbers.


The PS3 soon rebounded, however, and with a retooled interior design (which now lacked the processor chips necessary to run PlayStation 2 games) it also became much smaller and cheaper than its launch model. The DualShock 3 controller added force-feedback support to the original SixAxis, while the PlayStation Move controller challenged Wii MotionPlus and Kinect.


According to an IDC report, after being on the market about half as long as the PlayStation 2 the PS3 has sold roughly half as many consoles, with “about 77 million” sold.


2013 — The PlayStation 4?


Code-named “Orbis,” Sony’s next-generation PlayStation console is widely expected to be unveiled Wednesday. Dan Graziano of BGR News says that it may use a Move-enabled controller with a PS Vita-style touchpad, and that while it probably won’t be compatible with PS3 games it may be able to stream them online.


Jared Spurbeck is an open-source software enthusiast, who uses an Android phone and an Ubuntu laptop PC. He has been writing about technology and electronics since 2008.


Gaming News Headlines – Yahoo! News




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What's Next for Mindy McCready's Two Young Boys?















02/19/2013 at 07:00 PM EST



Mindy McCready's apparent suicide on Sunday has left her two young sons in custodial limbo.

The boys – Zander, 6, and Zayne, 10 months – had been in state custody since Feb. 7, when McCready called police to ask for help in making her father and stepmother leave her home. When police arrived, McCready appeared to be intoxicated, according to a Department of Human Services report.

In a subsequent petition, the singer's father, Tim McCready, asked the court to order her to undergo mental health and substance abuse evaluation and treatment, alleging that his daughter, who had recently lost her boyfriend, "hasn't had a bath in a week ... screams about everything ... [is] very verbally abusive to Zander."

After a judge granted the petition, the children were quickly removed and placed into foster care. Although McCready was released from treatment, the boys remained in state custody.

At the time, Zander's father, Billy McKnight, requested custody of his son. "My son needs me," he told PEOPLE on Feb. 8. "I'm married, working and successful. I'm on the right track and proud of it. I've been sober for years. I just want my son."

But McCready's mother and stepfather, Gayle and Michael Inge, also want custody of the children – and authorities seem to agree.

In a proposed order sent to Circuit Judge Lee Harrod, the Department of Human Services proposed that the Inges might be a better fit for the children, claiming that they have "a substantial relationship." The Inges had custody of Zander for much the past few years, during McCready’s rehab and jail stints.

With McCready's death, the judge will have to determine what is in the children's best interest. A custody hearing has been scheduled for April 5.

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Drug overdose deaths up for 11th consecutive year


CHICAGO (AP) — Drug overdose deaths rose for the 11th straight year, federal data show, and most of them were accidents involving addictive painkillers despite growing attention to risks from these medicines.


"The big picture is that this is a big problem that has gotten much worse quickly," said Dr. Thomas Frieden, head of the Centers for Disease Control and Prevention, which gathered and analyzed the data.


In 2010, the CDC reported, there were 38,329 drug overdose deaths nationwide. Medicines, mostly prescription drugs, were involved in nearly 60 percent of overdose deaths that year, overshadowing deaths from illicit narcotics.


The report appears in Tuesday's Journal of the American Medical Association.


It details which drugs were at play in most of the fatalities. As in previous recent years, opioid drugs — which include OxyContin and Vicodin — were the biggest problem, contributing to 3 out of 4 medication overdose deaths.


Frieden said many doctors and patients don't realize how addictive these drugs can be, and that they're too often prescribed for pain that can be managed with less risky drugs.


They're useful for cancer, "but if you've got terrible back pain or terrible migraines," using these addictive drugs can be dangerous, he said.


Medication-related deaths accounted for 22,134 of the drug overdose deaths in 2010.


Anti-anxiety drugs including Valium were among common causes of medication-related deaths, involved in almost 30 percent of them. Among the medication-related deaths, 17 percent were suicides.


The report's data came from death certificates, which aren't always clear on whether a death was a suicide or a tragic attempt at getting high. But it does seem like most serious painkiller overdoses were accidental, said Dr. Rich Zane, chair of emergency medicine at the University of Colorado School of Medicine.


The study's findings are no surprise, he added. "The results are consistent with what we experience" in ERs, he said, adding that the statistics no doubt have gotten worse since 2010.


Some experts believe these deaths will level off. "Right now, there's a general belief that because these are pharmaceutical drugs, they're safer than street drugs like heroin," said Don Des Jarlais, director of the chemical dependency institute at New York City's Beth Israel Medical Center.


"But at some point, people using these drugs are going to become more aware of the dangers," he said.


Frieden said the data show a need for more prescription drug monitoring programs at the state level, and more laws shutting down "pill mills" — doctor offices and pharmacies that over-prescribe addictive medicines.


Last month, a federal panel of drug safety specialists recommended that Vicodin and dozens of other medicines be subjected to the same restrictions as other narcotic drugs like oxycodone and morphine. Meanwhile, more and more hospitals have been establishing tougher restrictions on painkiller prescriptions and refills.


One example: The University of Colorado Hospital in Aurora is considering a rule that would ban emergency doctors from prescribing more medicine for patients who say they lost their pain meds, Zane said.


___


Stobbe reported from Atlanta.


___


Online:


JAMA: http://www.jama.ama-assn.org


CDC: http://www.cdc.gov


___


AP Medical Writer Lindsey Tanner can be reached at http://www.twitter.com


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M&A deals lift Wall Street shares nearer a record high

NEW YORK (Reuters) - U.S. stocks rose on Tuesday as this year's ongoing surge in merger activity suggested investors were still finding value in the market even as indexes closed in on all-time highs.


Office Depot Inc surged 9.4 percent to $5.02 after a person familiar with the matter said the No. 2 U.S. office supply retailer was in advanced talks to merge with smaller rival OfficeMax Inc , which jumped more than 20 percent.


News of the potential move came just days after Berkshire Hathaway and a partner agreed to acquire H.J. Heinz Co for $23 billion, and following a revised $20 billion takeover of Mexican brewer Grupo Modelo by Anheuser-Busch InBev .


Deal activity has helped equities resist a pullback as investors use dips in stocks as buying opportunities. The S&P is up about 7 percent so far in 2013 and has climbed for the past seven weeks in its longest weekly winning streak since January 2011, though most of the weekly gains have been slim.


The Dow industrials closed 0.9 percent away from their record high while S&P 500 was 2.2 percent off its peak.


"Deals are good for the market," said Frank Lesh, a futures analyst and broker at FuturePath Trading LLC in Chicago. "The fact that they're being done is a positive."


More than $158 billion in deals has been announced so far in 2013, more than double the activity in the same period last year and accounting for 57 percent of global deal volumes, according to Thomson Reuters Deals Intelligence.


The Dow Jones industrial average <.dji> gained 53.91 points, or 0.39 percent, to 14,035.67. The Standard & Poor's 500 Index <.spx> gained 11.15 points, or 0.73 percent, to 1,530.94. The Nasdaq Composite Index <.ixic> gained 21.56 points, or 0.68 percent, to 3,213.59.


Other stocks in the office supplies sector also rose. Larger rival Staples Inc shot up 13.1 percent to $14.65 as the best performer on the S&P 500.


"Equity investors have to be encouraged by M&A since, if the number crunchers are offering large premiums, that shows how much value is still in the market," said Mike Gibbs, co-head of the equity advisory group at Raymond James in Memphis, Tennessee.


On the downside, health insurance stocks tumbled, led by a 6.4 percent drop in Humana Inc to $73.01. The company said the government's proposed 2014 payment rates for Medicare Advantage participants were lower than expected and would hurt its profit outlook.


UnitedHealth Group lost 1.2 percent to $56.66. The Morgan Stanley healthcare payor index <.hmo> dropped 1.2 percent.


Wall Street's strong start to the year was fueled by better-than-expected corporate earnings, as well as a compromise in Washington that temporarily averted automatic spending cuts and tax hikes that are predicted to damage the economy.


The compromise on across-the-board spending cuts postponed the matter until March 1, at which point the cuts take effect. Ahead of the debate over the cuts, known as sequestration, further gains for stocks may be difficult to come by.


Some investors say the debate could be the catalyst for a long anticipated sell-off after the market's recent strong run.


Carter Worth, a technical analyst at Oppenheimer, pointed to the "especially complacent action of the past six weeks," noting that, as of Friday, stocks have gone 33 sessions without a dip of more than 1.5 percent.


"We would be selling aggressively into the market's current strength," he said in a research note.


Economic data showed the NAHB/Wells Fargo Housing Market index unexpectedly edged down to 46 in February from 47 in the prior month as builders faced higher material costs.


According to the Thomson Reuters data through Monday morning, of the 391 companies in the S&P 500 that have reported results, 70.1 percent have exceeded analysts' expectations, compared with a 62 percent average since 1994 and 65 percent over the past four quarters.


Fourth-quarter earnings for S&P 500 companies have risen 5.6 percent, according to the data, above a 1.9 percent forecast at the start of the earnings season.


Express Scripts rose 2.5 percent to $56.98 after the pharmacy benefits manager posted fourth-quarter earnings.


About two stocks rose for everyone that fell on the New York Stock Exchange and Nasdaq. About 6.48 billion shares changed hands on the New York Stock Exchange, the Nasdaq and NYSE MKT, in line with the daily average so far this year.


(Additional reporting by Chuck Mikolajczak Ryan Vlastelica and Rodrigo Campos; Editing by Chizu Nomiyama, Kenneth Barry and Nick Zieminski)



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Oslo Journal: In Norway, TV Program on Firewood Elicits Passions


Kyrre Lien for The New York Times


Lars Mytting at his home in Elverum, Norway. His best-selling book, “Solid Wood: All About Chopping, Drying and Stacking Wood — and the Soul of Wood-Burning” inspired a TV program about cutting, stacking and burning firewood.







OSLO — The TV program, on the topic of firewood, consisted mostly of people in parkas chatting and chopping in the woods and then eight hours of a fire burning in a fireplace. Yet no sooner had it begun, on prime time on Friday night, than the angry responses came pouring in.




“We received about 60 text messages from people complaining about the stacking in the program,” said Lars Mytting, whose best-selling book “Solid Wood: All About Chopping, Drying and Stacking Wood — and the Soul of Wood-Burning” inspired the broadcast. “Fifty percent complained that the bark was facing up, and the rest complained that the bark was facing down.”


He explained, “One thing that really divides Norway is bark.”


One thing that does not divide Norway, apparently, is its love of discussing Norwegian wood. Nearly a million people, or 20 percent of the population, tuned in at some point to the program, which was shown on the state broadcaster, NRK.


In a country where 1.2 million households have fireplaces or wood stoves, said Rune Moeklebust, NRK’s head of programs in the west coast city of Bergen, the subject naturally lends itself to television.


“My first thought was, ‘Well, why not make a TV series about firewood?’” Mr. Moeklebust said in an interview. “And that eventually cut down to a 12-hour show, with four hours of ordinary produced television, and then eight hours of showing a fireplace live.”


There is no question that it is a popular topic. “Solid Wood” spent more than a year on the nonfiction best-seller list in Norway. Sales so far have exceeded 150,000 copies — the equivalent, as a percentage of the population, to 9.5 million in the United States. — not far below the figures for E. L. James’s Norwegian hit “Fifty Shades Fanget,” proof that thrills come in many forms.


“National Firewood Night,” as Friday’s program was called, opened with the host, Rebecca Nedregotten Strand, promising to “try to get to the core of Norwegian firewood culture — because firewood is the foundation of our lives.” Various people discussed its historical and personal significance. “We’ll be sawing, we’ll be splitting, we’ll be stacking and we’ll be burning,” Ms. Nedregotten Strand said.


But the real excitement came when the action moved, four hours later, to a fireplace in a Bergen farmhouse.


Perhaps you have seen a log fire burning on television before. But it would be very foolish to confuse Norway’s eight-hour fireplace extravaganza on Friday with the Yule log broadcast in the United States at Christmastime.


While the Yule log fire plays on a constant repeating loop, the fire on “National Firewood Night” burned all night long, in suspensefully unscripted configurations. Fresh wood was added through the hours by an NRK photographer named Ingrid Tangstad Hatlevoll, aided by viewers who sent advice via Facebook on where exactly to place it.


For most of the time, the only sound came from the fire. Ms. Hatlevoll’s face never appeared on screen, but occasionally her hands could be seen putting logs in the fireplace, or cooking sausages and marshmallows on sticks.


“I couldn’t go to bed because I was so excited,” a viewer called niesa36 said on the Dagbladet newspaper Web site. “When will they add new logs? Just before I managed to tear myself away, they must have opened the flue a little, because just then the flames shot a little higher.


“I’m not being ironic,” the viewer continued. “For some reason, this broadcast was very calming and very exciting at the same time.”


To be fair, the program was not universally acclaimed. On Twitter, a viewer named Andre Ulveseter said: “Went to throw a log on the fire, got mixed up, and smashed it right into the TV.”


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Sony slashes PS Vita pricing in Japan ahead of PlayStation 4 unveiling






As Sony’s (SNE) struggles continue in the portable gaming market, the consumer electronics giant announced on Monday that it will slash the price of its PlayStation Vita console in Japan. Beginning late next week, both the Wi-Fi-only and 3G-connected versions of the Vita will drop to 19,980 yen including taxes, or $ 215.42 USD at Monday’s exchange rate. The Wi-Fi model currently costs 24,980 yen ($ 269.33 USD) and the 3G model is priced at 29,980 yen ($ 323.24 USD) until February 28th when the price drops take effect. Sony hasn’t said anything about cutting the cost of the portable console outside of Japan, but it may make some announcements during its PlayStation 4 event on Wednesday. The company’s full press release follows below.



PlayStation ® Vita price revision
February 28, 2013 (Thursday) retail price of 19,980 yen (tax included)






[More from BGR: BlackBerry 10 browser smokes iOS 6 and Windows Phone 8 in comparison test [video]]


February 28, 2013 (Thursday), ¥ 29,980 traditional Sony Computer Entertainment Japan ※ 1 (SCEJ) is, 3G/Wi-Fi model (including tax, the retail price of the PlayStation ® Vita (PS Vita below) to 19,980 yen including tax) (, Wi-Fi model will be revised (including tax) from 19,980 yen (including tax) from 24,980 yen).


By addition to the GPU and the CPU, high-performance display and a beautiful that, with such dual analog stick and the multi-touch pad on the rear panel, PS Vita, which was launched in December 2011, to deliver an immersive experience of the ultimate I will continue to provide the gaming experience. In addition to the expansion of an attractive color variations such as sapphire Cosmic Red and Blue, by the system of free software updates, such as service response to PlayStation ® Plus ※ 2 software and standard flat-rate “PlayStation” first, PS Vita users meet the needs of everyone in, I’m constantly evolving. In addition to the methods existing Wi-Fi, by which supports access to the 3G network a new, PS Vita has realized the connection of new and everyone other users in everyday life. To enjoy the PS Vita to everyone more users, we will begin offering at a price of ¥ 19,980 revision both models. As a result, the user’s everyone, you can feel free to choose the model that is appropriate for the game play style of your choice is available.


In addition, we received strong support from companies like software maker, dedicated software is PS Vita PS Vita interactive content that can be enjoyed by more than 100, you can download from the PlayStation ® Store has reached more than 1,500 ※ 3 at the end of January 2013 You had to. Our company and our future than software manufacturers, “Den 討鬼” (SEGA) “Phantasy Star Online 2″, “SOUL SACRIFICE (Soul Sacrifice)” (TECMO KOEI GAMES CO., LTD.) Sony Corporation (- from hunting action game to enjoy cooperative play, such as Computer Entertainment), the player taking the communication meeting, “Kagura 閃乱 SHINOVI VERSUS – proof of the girls” – “Oboro Muramasa”, Marvelous AQL), ​​”Tales Inc. ( Obuhatsu Pirate Musou 2 R “,” One Piece Baseball Spirits 2013 “(NAMCO BANDAI Games Inc.)” “to work, such as the long-awaited game fans (Konami Digital Entertainment Co., Ltd.), is expected to be released one after another title is scheduled.


(Thursday), the set body and PS Vita special edition with the motif of the peripherals, the same title, and a variety of breaking down the common sense of the multi-Hunting Action “(Soul Sacrifice) SOUL SACRIFICE” March 7, 2013 change (including tax) 24,980 yen, will be released in limited quantities from (tax included) for a suggested retail price of 29,980 yen originally planned, did the “PlayStation ® Vita SOUL SACRIFICE PREMIUM EDITION”.


We will carry out a variety of campaigns to suit this price revision, to everyone in the user’s enjoy PS Vita. Please refer to the following for the campaign details.


So that you can enjoy the world of entertainment unique PS Vita to more customers in the future, SCEJ will continue to strongly promote and expand further spread of the PS Vita platform.



Gaming News Headlines – Yahoo! News





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Mindy McCready: Under Police Scrutiny at Time of Suicide?















02/18/2013 at 06:00 PM EST







Mindy McCready and David Wilson


Courtesy Mindy McCready


When Mindy McCready talked to police in recent weeks, her account of how her boyfriend came to be found with a fatal gunshot wound to the head concerned police, a law enforcement source tells PEOPLE.

"At first, she said she hadn't heard the gunshot because the TV was too loud. Then she said she had heard the gunshot," the source says. "So obviously there were a lot of questions, and the Sheriff was asking for clarification."

But before investigators could re-interview her, the long-troubled country singer also would die under eerily similar circumstances, her body discovered at the same Heber Springs, Ark., house just feet away from where David Wilson died.

McCready's death was blamed on what "appears to be a single self-inflicted gunshot wound," the Cleburne County Sheriff's Office said in a statement.

This differed from how the sheriff characterized Wilson's case. His cause and manner of death still have not been established by the coroner. It was McCready's publicist, and not a law enforcement official, who announced that Wilson had died of a self-inflicted gunshot wound.

After Wilson's death, McCready, 37, spoke to investigators three times, but they didn't feel as if they were through with her.

"At no point did [police] tell her she was a suspect, and she wasn't officially one," says the source. "But she knew that some of her answers didn't stand up to questioning. She was very cooperative, but she just wasn't making a lot of sense."


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Hip implants a bit more likely to fail in women


CHICAGO (AP) — Hip replacements are slightly more likely to fail in women than in men, according to one of the largest studies of its kind in U.S. patients. The risk of the implants failing is low, but women were 29 percent more likely than men to need a repeat surgery within the first three years.


The message for women considering hip replacement surgery remains unclear. It's not known which models of hip implants perform best in women, even though women make up the majority of the more than 400,000 Americans who have full or partial hip replacements each year to ease the pain and loss of mobility caused by arthritis or injuries.


"This is the first step in what has to be a much longer-term research strategy to figure out why women have worse experiences," said Diana Zuckerman, president of the nonprofit National Research Center for Women & Families. "Research in this area could save billions of dollars" and prevent patients from experiencing the pain and inconvenience of surgeries to fix hip implants that go wrong.


Researchers looked at more than 35,000 surgeries at 46 hospitals in the Kaiser Permanente health system. The research, published Monday in JAMA Internal Medicine, was funded by the U.S. Food and Drug Administration.


After an average of three years, 2.3 percent of the women and 1.9 percent of the men had undergone revision surgery to fix a problem with the original hip replacement. Problems included instability, infection, broken bones and loosening.


"There is an increased risk of failure in women compared to men," said lead author Maria Inacio, an epidemiologist at Southern California Permanente Medical Group in San Diego. "This is still a very small number of failures."


Women tend to have smaller joints and bones than men, and so they tend to need smaller artificial hips. Devices with smaller femoral heads — the ball-shaped part of the ball-and-socket joint in an artificial hip — are more likely to dislocate and require a surgical repair.


That explained some, but not all, of the difference between women and men in the study. It's not clear what else may have contributed to the gap. Co-author Dr. Monti Khatod, an orthopedic surgeon in Los Angeles, speculated that one factor may be a greater loss of bone density in women.


The failure of metal-on-metal hips was almost twice as high for women than in men. The once-popular models were promoted by manufacturers as being more durable than standard plastic or ceramic joints, but several high-profile recalls have led to a decrease in their use in recent years.


"Don't be fooled by hype about a new hip product," said Zuckerman, who wrote an accompanying commentary in the medical journal. "I would not choose the latest, greatest hip implant if I were a woman patient. ... At least if it's been for sale for a few years, there's more evidence for how well it's working."


___


Online:


Journal: http://www.jamainternalmed.com


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